Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Patent
1999-12-27
2000-11-28
Prouty, Rebecca E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
435195, 424 946, C12N 914, A61K 3846
Patent
active
061533971
ABSTRACT:
The present invention relates to arthropod epoxide hydrolase proteins; to arthropod epoxide hydrolase nucleic acid molecules, including those that encode such epoxide hydrolase proteins; to antibodies raised against such epoxide hydrolase proteins; and to other compounds that inhibit arthropod epoxide hydrolase activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from hematophagous arthropod infestation.
REFERENCES:
patent: 5445956 (1995-08-01), Hammock et al.
Khlebodarova et al., 1996, "A Comparative Analysis of Juvenile Hormone Metabolyzing Enzymes in Two Species of Drosophila During Development," Insect Biochem. Molec. Biol., vol. 26:8-9, pp. 829-835.
Roe et al., 1996, "Mechanism of Action and Cloning of Epoxide Hydrolase From the Cabbage Looper, Trichoplusia ni," Archives of Insect Biochemistry and Physiology, vol. 32, pp. 527-535.
Touhara et al., 1993, "Juvenile Hormone Epoxide Hydrolase," The Journal of Biological Chemistry, vol. 268:26, pp. 19604-19609.
Wojtasek et al., 1996, "An Insect Juvenile Hormone--Specific Epoxide Hydrolase Is Related to Vertebrate Microsomal Epoxide Hydrolases," Biochemical and Biophysical Research Communications vol. 220, pp. 323-329.
Debernard et al., 1998, "Expression and Characterization of the Recombinant Juvenile Hormone Epoxide Hydrolase (JHEH) From Manduca sexta, " Insect Biochemistry and Molecular Biology, vol. 28, pp. 409-419.
Jacobson, et al., 1972, Insect Juvenile Hormones; Chemistry and Action, Academic Pres (Menn J J and Beroza M, Eds.), New York, pp. 249-302.
Takigawa, et al., Jul. 1979, Agricultural and Biological Chemistry, vol. 43, No. 7, pp. 1591-1594.
Brandt Kevin S.
Lo Katherine Callies
Silver Gary M.
Wisnewski Nancy
Heska Corporation
Prouty Rebecca E.
Slobodyansky Elizabeth
LandOfFree
Flea epoxide hydrolase proteins and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Flea epoxide hydrolase proteins and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Flea epoxide hydrolase proteins and uses thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1723826