Flea aminopeptidase nucleic acid molecules and uses thereof

Details Flea aminopeptidase nucleic acid molecules and uses thereof Flea aminopeptidase nucleic acid molecules and uses thereof

1997-08-05

2000-06-20

Allen, Marianne P.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 232, 4352351, 4353201, C12N 1552, C12N 1557, C12N 701

Patent

active

060776870

ABSTRACT:
The present invention relates to flea serine protease proteins, aminopeptidase proteins and flea cysteine protease proteins; to flea serine protease, aminopeptidase and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease, aminopeptidase and/or cysteine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.

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