Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-06-14
2011-06-14
Levy, Neil (Department: 1615)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S456000, C514S861000, C514S887000, C424S059000, C424S070100, C424S401000
Reexamination Certificate
active
07960430
ABSTRACT:
The invention relates to complexes of certain flavonoid derivatives, of the formula I compositions which comprise such derivatives, corresponding processes for the preparation of the flavonoid derivatives or of compositions comprising same, and the use thereof, in particular for the care, preservation or improvement of the general state of the skin or hair. Formula (1), in which Z1to Z4and Z6to Z10each, independently of one another, denote H, OH, CH3COO, alkoxy, hydroxyalkoxy, mono- or oligoglycoside radicals and where the alkoxy and hydroxyalkoxy groups may be branched and unbranched and can have 1 to 18 C atoms. Formula (II) denotes, Z5is a mono- or the oligoglycoside radical, where bonded to this glycoside radical, in each case via an —O— group, is at least one radical selected from certain benzo molecule.
REFERENCES:
patent: 5472954 (1995-12-01), Loftsson
patent: 2003/0105031 (2003-06-01), Rosenbloom
patent: 2004/0081675 (2004-04-01), Wirth et al.
patent: 2007/0020350 (2007-01-01), Numano et al.
patent: 0 796 624 (1997-09-01), None
patent: 59-137 499 (1984-08-01), None
patent: 2-268643 (1990-11-01), None
patent: 05-186 344 (1993-07-01), None
patent: 07-075 536 (1995-03-01), None
patent: WO 02/069926 (2002-09-01), None
patent: WO 02/069926 (2002-09-01), None
Sala et al. Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside, European Journal of Pharmacology, 461, 53-61, 2003.
Christoff et al. Dynamics of Complexation of flavone and chromone to B-cyclodextrin, Journal of Photochemistry and Photobiology A: Chemistry 134, 169-176, 2000.
Buschmann et al. Applications of cyclodextrins in cosmetic products: A review, Journal of Cosmetic Science, 53, 185-191, 2002.
Hostettmann et al. A Study of the Cyclodextrin Complexes of Flavonoids and Azodyes by Thin Layer Chromatography. Part II. Hydroxyproply-cyclodextrins, Phytochemical Analysis, 11, 380-382, 2000.
Miyake et al. Improvement of Solubility and Oral Bioavailability of Rutin by Complexation with 2-Hydroxypropyl-B-cyclodextrin, Pharmaceutical Development and Technology, 5(3), 399-407, 2000.
Ficarra et al. Study of Flavonoids/B-cyclodextrins inclusion complexes by NMR, FT-IR, DSC, X-ray investigation, Journal of Pharmaceutical and Biomedical Analysis, 29, 1005-1014, 2002.
Wollenberg et al., Tropical Immunomodulatory Agents and Their Targets in Inflammatory Skin Diseases, Transplantation Proceedings 2001, pp. 2212-2216.
Buschmann H-J et al: “Applications of Cyclodextrins in Cosmetic Products: A Review” Journal of Cosmetic Science, Society of Cosmetic Chemists, New York, NY, US, Bd. 53, Nr. 3, May 2002, pp. 185-191, XP008013888; ISSN: 1525-7886.
Loftsson T et al: “Cylodextrins in Topical Drug Formulations: Theory and Practice” Internaional Journal of Pharmaceutics, Amsterdam, NL., Bd. 225, Nr. 1/2, Aug. 2001; pp. 15-30, XP001023910; ISSN: 0378-5173.
K. Miyake, et al.: “Improvement of Solubility and Oral Bioavailability of Rutin by Complexation With 2-Hydroxypropyl-β-Cyclodextrin” Pharmaceutical Development and Technology, 5(3), pp. 399-407 (2000).
Nguyen, et al.: “Study of Inclusion Compounds of Rutin” Congr. in. Technol. Pharm., 6th(1992), vol. 5, pp. 408-416.
Dimova, et al.: “Safety-Assessment of 3-Methoxyquercetin as an Antirhinoviral Compound for Nasal Application: Effect on Ciliary Beat Frequency”, Int. J. Pharm. 263 (2003), pp. 95-103.
Ficarra, et al.: “Study of Flavonoids/β-Cyclodextrins Inclusion Complexes by NMR, FT-IR, DSC, X-Ray Investigation”, J. Pharm. Biomed. Analysis 29 (2002), pp. 1005-1014.
Wang, et al.: “Enhanced Solubility of Flavonoids by Inclusion With β-Cyclodextrin and its Derivatives”, Chin. J. Applied Chem., vol. 19, (2002), pp. 702-704.
Hostettmann, et al.: “A Study of the Cyclodextrin Complexes of Flavonoids and AZO-Dyes by Thin Layer Chromatography. Part II. Hydroxypropylcyclodextrins”, Phytochemical Analysis, vol. 11, pp. 380-382 (2000).
Buchholz Herwig
Rosskopf Ralf
Wirth Corinna
Levy Neil
Merck Patent GmbH
Millen White Zelano & Branigan P.C.
LandOfFree
Flavonoid complexes with cyclodextrins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Flavonoid complexes with cyclodextrins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Flavonoid complexes with cyclodextrins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2728375