Flavene and thioflavene derivatives

Details Flavene and thioflavene derivatives Flavene and thioflavene derivatives

1984-08-24

1987-05-12

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 62, 544145, 544151, 546196, 546202, 549 23, 549398, 549400, 549403, 549404, 549406, C07D40504, C07D30934, C07D33506

Patent

active

046652027

ABSTRACT:
The invention relates to pharmaceutical preparations containing compounds of formula I ##STR1## in which X.sub.1 and X.sub.2, independently of each other, represent hydrogen, halogen, unsubstituted or substituted amino or a quaternary ammonium salt; etherified or esterified hydroxy; free, etherified, esterified or oxidized mercapto; nitro; functionally modified formyl; free or functionally modified carboxyl; acyl; an unsubstituted or substituted hydrocarbon radical, or an unsubstituted or substituted heterocyclic radical; with the proviso that at least one of the radicals X.sub.1 and X.sub.2 is bonded by a carbon atom to the ring system and with the proviso that X.sub.1 and X.sub.2 cannot be together halogen and formyl; in which Y represents oxygen, sulfur, sulfinyl or sulfonyl but must be sulfur, sulfinyl or sulfonyl, if X.sub.1 is hydrogen and X.sub.2 is formyl, and the rings A and B are each unsubstituted or substituted; or pharmaceutically acceptable salts of such compounds that contain a salt-forming group, and to novel compounds of formula I. The compounds are useful e.g. for the treatment of diseases of the respiratory tract and of liver diseases. The are prepared by methods known per se.

REFERENCES:
patent: 3567605 (1971-03-01), Becker
patent: 3796727 (1974-03-01), Debder
Rene, et al., Eur. J. Med. Chem-Chimica Therapeutica, Jan.-Feb. 1975, vol. 10, No. 1, pp. 72-78.
Fatome, et al., Eur. J. Med. Chem.-Chimica Therapeutica Jan.-Feb. 1976, vol. 11, pp. 81-82.
Bird, et al., J. Chem. Soc. 1, 1983, pp. 1831-1846.
CA 97: 98046v: Extractive Concentration of Ultramicro Quantity of Tungsten in Water.
Sartori, et al., J. Org. Chem., vol. 44, No. 5, 1979, pp. 803-805.
Oluwadiya, et al., J. Chem. Soc., 1978, pp. 88-92.
Olenovich, et al., Zhurnal Analiticheskoi Khimii, vol. 32, No. 12, pp. 2346-2351.
Ostensen, et al., Acta Chemica Scandinavica B31 (1977), 496-500.
Ostensen, et al., Acta Chemica Scandinavica B30 (1976), 635-639.
Badran, et al., J. Chem. Soc. 1976, pp. 1389-1392.
Mishrikey, et al., Acta Chemica Scandinaavica B30 (1976), 329-335.
Ostensen, et al., Acta Chemica Scandinavica B29 (1975), 1067-1070, 1075-1078.
Cullen, et al., J. Chem. Soc. 1975, pp. 1671-1674.
Bennett, et al., J. Chem. Soc. 1973, pp. 688-691.
Olaniyi, et al., J. Chem. Soc. 1973, pp. 179-184.
Bradomante, et al., J. Chem. Soc. 1973, pp. 163-166.
Cullen, et al., J. Chem. Soc. 1971, pp. 2848-2855.
Poluektov, et al., Zhunal Analiticheskoi Khimii, vol. 25, No. 5, pp. 899-903, May 1970.
Cotterill, et al., J. Chem. Soc. 1970, pp. 1758-1764.
Nazarenko, et al., Chemistry of Reactions Between Ions of Multivitamins Elements and Organic Reagents, pp. 620-626.
Nazarenko, et al., The Chemistry of the Reactions Between Multivitamin Element Ions And Organic Reagents, pp. 1460-1463.
Weinges, et al., Liebigs Ann. Chem., vol. 711, pp. 184-204, (1968).
Weiges, et al., Chem. Ber., vol. 103, pp. 2344-2349, (1970).
Weinges, CA 79: 42289n (1973).
Girardin, et al., CA 83: 28053g, (1975).

Affiliated with

Also associated with

Rating

Flavene and thioflavene derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Flavene and thioflavene derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Flavene and thioflavene derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1803527