Flavanone compound and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C252S404000, C549S403000

Reexamination Certificate

active

10562019

ABSTRACT:
Each of an antioxidant, an antimicrobial agent, an antitumor agent, a food and beverage product, cosmetics, a quasi-drug and a pharmaceutical of the present invention contains a new flavanone compound represented by the following structural formula:Alternatively, each of an antioxidant, an antimicrobial agent, an antitumor agent, a food and beverage product, cosmetics, a quasi-drug and a pharmaceutical of the present invention contains at least one flavanone compound selected from the group consisting of nymphaeol-A, nymphaeol-B, and nymphaeol-C.

REFERENCES:
patent: 4885298 (1989-12-01), Rimbault
Fujimoto, Takunori et al., Diversity of propolis., Part 2., Propolis from Japan, Honeybee Science, 2001, 22, No. 2, pp. 67-74.
Phillips, William R. et al., C-Geranyl Compunds from Mimulus clevelandii, J. Nat. Prod., 1996, vol. 59, pp. 495 to 497.
Yakushijin, Kenichi et al., New Prenylflavanones From Hernandia Nymphaefolia (PRESL) Kubitzki, Heterocycles, 1980, vol. 14, No. 4, pp. 397 to 402.
Burdock, G.A., Review of the Biological Properties and Toxicity of Bee Propolis (Propolis), Food and Chemical Toxicology, 1998, vol. 36, pp. 347 to 363.
Masuda, Toshiya et al., Flow Cytometric Estimation on Cytotoxic Activity of Leaf Extracts from Seashore Plants in Subtropical Japan: Isolation, Quantification and Cytotoxic Action of (-)-Deoxypodophyllotoxin, Phytotherapy Research, 2002, vol. 16, pp. 353 to 358.
Tseng, Mei-Huims et al., Allelopathic Prenylflavanones from the Fallen Leaves ofMacaranga tanarius, J. Nat. Prod. 2001, vol. 64, pp. 827 to 828.
Tseng et al.; “Allelopathic Potential of Macaranga Tanarius (L.) Muell. -ARG.”, Journal of Chemical Ecology, vol. 29, No. 5, pp. 1269-1286 (May 2003).
Chen et al.; “Cytotoxic Prenylflavanones From Taiwanese Propolis”; Journal of Natural Products, vol. 66, No. 4, pp. 503-506 (2003)

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