Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-04-14
2009-12-29
Andres, Janet L. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S456000, C514S457000, C514S458000, C549S389000, C549S390000, C549S392000, C549S403000
Reexamination Certificate
active
07638554
ABSTRACT:
Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I)wherein R1through R3and R5through R11are defined herein, and α, β and γ are optional bonds, providing that when α is absent, β is present, and when β is absent, α is present. When α is present, preferred R4moieties are selected from O, S, NH and CH2, and when α is absent, preferred R4groups are selected from OH, SH, NH2and CH3. When γ is present, the preferred R5substituent is O, while when γ is absent, the preferred R5substituent is OH. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.
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Waleh Nahid
Zaveri Nurulain T.
Andres Janet L.
Covington Raymond
Mintz Levin Cohn Ferris Glovsky & Popeo PC
Rutenberg Issac M.
SRI - International
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