FK-506 type macrolide intermediate

Details FK-506 type macrolide intermediate FK-506 type macrolide intermediate

1992-02-19

1993-08-10

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548533, C07D20708

Patent

active

052350665

ABSTRACT:
An intermediate, useful in the conversion of FK-506 to FK-525 and analogous 23-membered ring macrolides, of the structure: ##STR1##

REFERENCES:
patent: 5011943 (1991-04-01), Wang
patent: 5087703 (1992-02-01), Volante et al.
J. Am. Chem. Soc., 109, pp. 5031-5033, (1987), Tanaka, et al.
J. Am. Chem. Soc., 111, pp. 1157-1159, (1989), Jones, et al.

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