FK 228 derivates as HDAC inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S183000, C530S317000, C530S323000

Reexamination Certificate

active

07977304

ABSTRACT:
Compounds which are FK228 analogues of the general formula (I) or (I′), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3and R4are the same or different and represent an amino acid side chain moiety and each R6is the same or different and represents hydrogen or C1-C4alkyl.

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