Fixation of enzymes with bis-dithioesters

Details Fixation of enzymes with bis-dithioesters Fixation of enzymes with bis-dithioesters

1986-04-18

1988-08-30

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an...

435181, C12N 1114, C12N 1106

Patent

active

047677066

ABSTRACT:
Enzymes are fixed on carriers with a bis-dithioester capable of combining with the enzyme and with the carrier. The bis-dithioester has at each of its ends a group capable of reacting with an aimine function. The enzyme may be contacted with the bis-dithioester before the enzyme and carrier are combined. The carrier is an inorganic or organic solid.

REFERENCES:
patent: 3669841 (1972-06-01), Miller
patent: 4176006 (1979-11-01), Cormier et al.
patent: 4287345 (1981-09-01), Kotani et al.
patent: 4367309 (1983-01-01), Kondo et al.
Borlaza, et al., Carbohydrate Research, No. 1, vol. 68, 1979, pp. 141-143.
Borlaza, et al., Carbohydrate Research, vol. 79, 1980, pp. 125-132.
Marvel et al, J. Am. Chem. Soc. 77, pp. 5997-5999, Nov. 30, 1955.

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