Five-membered heterocyclic compounds

Details Five-membered heterocyclic compounds Five-membered heterocyclic compounds

2008-05-06

2008-05-06

Anderson, Rebecca (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S215000, C548S225000, C548S233000, C548S243000, C548S245000, C548S247000, C514S374000, C514S376000, C514S377000, C514S378000, C514S380000

Reexamination Certificate

active

07368578

ABSTRACT:
The present invention provides a compound represented by the formula:wherein R1is an optionally substituted 5-membered heterocyclic group; X, Y and V are the same or different and each is a bond, an oxygen atom, a sulfur atom and the like; Q is a divalent hydrocarbon group having 1 to 20 carbon atoms; ring A is an aromatic ring optionally further having 1 to 3 substituents; Z is —(CH2)n-Z1- or -Z1-(CH2)n— (n is an integer of 0 to 8, Z1is a bond, an oxygen atom, a sulfur atom and the like); ring B is a nitrogen-containing heterocycle optionally further having 1 to 3 substituents; W is a bond or a divalent hydrocarbon group having 1 to 20 carbon atoms; R2is a hydrogen atom, a cyano group, —PO(OR9)(OR10) (R9and R10are the same or different and each is a hydrogen atom or an optionally substituted hydrocarbon group, and R9and R10are optionally bonded to form an optionally substituted ring) and the like, or a salt thereof, which has a superior adipose tissue weight decreasing action, a hypoglycemic action and a hypolipidemic action, and which is useful as an agent for the prophylaxis or treatment of obesity, diabetes mellitus, hyperlipidemia, impaired glucose tolerance, hypertension and the like.

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