Fish serine proteinase and their pharmaceutical and cosmetic...

Details Fish serine proteinase and their pharmaceutical and cosmetic... Fish serine proteinase and their pharmaceutical and cosmetic...

2005-01-25

2005-01-25

Leith, Patricia (Department: 1654)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

C514S002600

Reexamination Certificate

active

06846485

ABSTRACT:
Fish derived serine proteinases including trypsins and chymotrypsin derived from cod such as Atlantic cod is used for treating and/or preventing a variety of diseases and disorders such as inflammatory diseases, infectious diseases caused by viruses, bacteria and fungal species and diseases where a receptor binding mechanism is involved in the pathogenesis. Pharmaceutical and cosmetic compositions comprising the proteinases are described.

REFERENCES:
patent: 5958406 (1999-09-01), de Faire et al.
patent: 6232088 (2001-05-01), Franklin et al.
Asgeirsson et al., “Purification and characterization of trypsin from the poikilotherm Gadus morhua”,Eur. S. Biochem.vol. 180, pp 85-94, 1989.
Asgeirsson et al., “Structural and Kinetic Properties of Chymotrypsin from Atlantic Cod (Gadus Morhua). Comparison with Bovine Chymotrypsin”,Comp. Biochem. Pysiol., vol. 99B, No. 2, pp. 327-335, 1991.
Asgeirsson et al., “Properties of elastase from Atlantic cod, a cold-adapted proteinase”,Biochimica et Biophysica Acta, vol. 1164, pp. 91-100, 1993.
Gudmundsdottir et al, “Isolation and characterization of cDNAs from Atlantic cod encoding two different forms of trysinogen”, Eur. J. Biochem. vol. 217, 1993, p. 1091-1097.

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