Chemistry: analytical and immunological testing – Heterocyclic carbon compound – Hetero-o
Reexamination Certificate
2009-09-10
2010-12-21
Wallenhorst, Maureen M (Department: 1777)
Chemistry: analytical and immunological testing
Heterocyclic carbon compound
Hetero-o
C436S171000, C436S173000, C435S006120, C702S019000
Reexamination Certificate
active
07855080
ABSTRACT:
The invention provides a method for evaluating the accuracy of an oligonucleotide sample, specifically a sample containing a variety of oligonucleotides of potentially varying size and sequence. The method provides a fingerprint that can be used to evaluate the accuracy of a multi-oligonucleotide sample whether or not the sample contains differing oligonucleotides that have the same or about the same molecular weight.
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Elliott, Brian, Mass Spectrometry Analysis of Oligonucleotide Synthesis, 2005, downloaded from the Internet at http://www.idtdna.com/Support/Technical/TechnicalBulletinPDF/ Mass—Spectrometry—Analysis—of—Oligonucleotide—Syntheses.pdf on Sep. 11, 2009.
Hail, Mark E., Automated LC/MS Strategies for High-Throughput and Detailed Analysis of Oligonucleotides, presented at TIDES 2007, Las Vegas, NV, May 20-23, 2007 downloaded from the Internet at http://download.enovatia.com/download/tides—2007—novatia.pdf on Sep. 11, 2009.
Integrated DNA Technologies, Inc.
Petravich John A.
Wallenhorst Maureen M
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