Filter device and filter element comprising at least one...

Details Filter device and filter element comprising at least one... Filter device and filter element comprising at least one...

2005-03-01

2005-03-01

Kim, John (Department: 1723)

Liquid purification or separation

Filter

Within flow line or flow line connected close casing

C210S483000, C210S490000, C210S493100, C210S497010, C210S497100, C210S500350, C210S500380, C210S500410, C210S512100, C264S041000, C427S244000

Reexamination Certificate

active

06860393

ABSTRACT:
The present invention provides, in certain embodiments, a negatively charged microporous membrane comprising a porous substrate and a crosslinked coating having fixed negative charges. The crosslinked coating can be prepared, e.g., from a polymerized composition comprising an unsaturated monomer having an anionic group, an N-(hydroxymethyl)- and/or N-(alkoxymethyl)-acrylamide, a hydrophilic unsaturated monomer, and an initiator. The present invention further provides, in some embodiments, a negatively charged microporous membrane comprising a porous substrate and a crosslinked coating prepared from a polymerized composition comprising an unsaturated monomer having an anionic group, an N-(hydroxymethyl)- or N-(alkoxymethyl)-acrylamide, a polysaccharide, and an initiator. The membranes of the present invention are suitable for use in ion exchange chromatography, for example, in the separation and purification of positively charged species such as proteins.

REFERENCES:
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patent: 4617321 (1986-10-01), MacDonald
patent: 5021160 (1991-06-01), Wolpert
patent: 5783094 (1998-07-01), Kraus et al.
patent: 5843789 (1998-12-01), Nomura et al.
patent: 44 39 444 (1996-05-01), None
patent: 0 474 617 (1992-03-01), None
patent: WO 9614151 (1996-03-01), None
patent: WO 9817377 (1998-04-01), None

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