Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1987-11-25
1991-05-14
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
424465, 424470, 424493, 424495, 424497, 524 53, A61K 914
Patent
active
050154800
ABSTRACT:
Aqueous diffusion coating formulations suitable for use on pharmaceutical dosage forms comprising an admixture of an insoluble polymer component of a copolymer of ethylacrylate and methylmethacrylate and as a hydrophilic component the polysaccharide pullulan. When applied to the substrate of choice, said formulations provide coatings exhibiting good mechanical strength and flexibility.
REFERENCES:
patent: 4462982 (1984-07-01), Samejimal et al.
patent: 4650666 (1987-03-01), Izutsu et al.
patent: 4695467 (1987-09-01), Uemura et al.
patent: 4708874 (1987-11-01), De Haan et al.
Remington's Pharmaceutical Sciences, 17th Edition, 1985, Chapter 91, p. 1634.
K. Lehmann, Acta. Pharm. Fenn. 91, 225-238 (1982).
Pullulan:Production and Applications.
Pullulan, Features and Applications.
Childers Ray F.
Oren Peter L.
Seidler Werner M. K.
Eli Lilly and Company
Jones Joseph A.
Page Thurman K.
Prater P. L.
Whitaker Leroy
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