Film coated tablet compositions having enhanced disintegration c

Details Film coated tablet compositions having enhanced disintegration c Film coated tablet compositions having enhanced disintegration c

1996-10-30

1998-09-15

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

427 221, 514819, 424717, 424687, 424716, 424686, A61K 936, A61K 932, A61K 4738

Patent

active

058075801

ABSTRACT:
A pharmaceutical composition for oral administration comprising a film coated tablet exhibiting enhanced disintegration characteristics, said film coating comprising a hydrophilic film forming polymer such as hydroxypropyl methylcellulose and an alkaline agent wherein the alkaline agent reduces the disintegration time of the film coating by increasing the rate of removal of the film coating polymers.

REFERENCES:
patent: 4556552 (1985-12-01), Porter et al.
patent: 4629620 (1986-12-01), Lindahl et al.
patent: 4965072 (1990-10-01), Alexander et al.
patent: 5098715 (1992-03-01), McCabe et al.
patent: 5122385 (1992-06-01), Daher et al.
patent: 5178868 (1993-01-01), Malmqvist-Granlund et al.
patent: 5472712 (1995-12-01), Oshlack et al.
patent: 5505962 (1996-04-01), Sparks

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