Liquid purification or separation – Processes – Chromatography
Patent
1982-04-23
1984-08-28
Schofer, Joseph L.
Liquid purification or separation
Processes
Chromatography
521 38, B01D 1508, C08F22020
Patent
active
044683308
ABSTRACT:
A filler for liquid chromatography, said filler consisting essentially of a hydrophilic ion-exchanger obtained by copolymerizing a mixture of (A) 5 to 90% by weight of a polymerizable monomer containing one polymerizable double bond and at least one carboxyl group per molecule and having a hydrophobic parameter of not more than 2.3, (B) 10 to 95% by weight of a crosslinkable polymerizable monomer containing at least two polymerizable double bonds per molecule and having a hydrophobic parameter of not more than 2.3, and (C) 0 to 85% by weight of a monomer being different from the monomer (A), containing one polymerizable double bond per molecule and having a hydrophobic parameter of not more than 2.3; and a method for separating a biological material such as proteins, enzymes and amino acids by liquid chromatography using the aforesaid filler.
REFERENCES:
patent: 3957741 (1976-05-01), Rembaum et al.
patent: 4036788 (1977-07-01), Steckler
patent: 4128706 (1978-12-01), Seita et al.
patent: 4202775 (1980-05-01), Abe et al.
patent: 4243534 (1981-01-01), Bulbenko
Araki Yasuhiko
Kamiyama Fumio
Kohara Minoru
Nagata Mituo
Kulkosky Peter F.
Schofer Joseph L.
Sekisui Kagaku Kogyo Kabushiki Kaisha
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