Fill material for soft gelatin pharmaceutical dosage form contai

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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Details

424 7801, 424454, 424455, 424456, 5147723, 514781, A61K 948

Patent

active

059086360

ABSTRACT:
The present invention relates to a semi-solid fill material for a soft gelatin capsule containing a therapeutically effective amount of an antiflatulent. The semi-solid is sufficiently viscous so that it cannot be expelled readily at room temperature from the capsule with a syringe.

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patent: 5073384 (1991-12-01), Valentine et al.
patent: 5275822 (1994-01-01), Valentine et al.
A. Banga et al. "Incorporation of Simethicone into Syrupy or Clear Base Liquid Orals", Drug Dev. and Indust. Pharm.., Article 15 (5), 691-704 (1989).
Translation only of "1 Introduction" B. Lippold, Influence of Vehicle on Drug Action in Solution Type Methylnicotinate Ointments, Acta Pharma. Technol. 35 (3), 128-135 (1989).

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