Fill material for soft gelatin pharmaceutical dosage form

Details Fill material for soft gelatin pharmaceutical dosage form Fill material for soft gelatin pharmaceutical dosage form

1996-06-28

1999-07-06

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424454, 424455, 424456, 5147723, 514781, A61K 948

Patent

active

059194812

ABSTRACT:
The present invention relates to a substantially translucent, semi-solid fill material for a soft gelatin capsule containing a therapeutically effective amount of a pharmaceutical dissolved or suspended in the semi-solid. The semi-solid is sufficiently viscous so that it cannot be readily expelled at room temperature from the capsule with a syringe.

REFERENCES:
patent: 4028024 (1977-06-01), Moreland
patent: 4486412 (1984-12-01), Shah et al.
patent: 4708834 (1987-11-01), Cohen et al.
patent: 4734284 (1988-03-01), Terada et al.
patent: 4935243 (1990-06-01), Borkan et al.
patent: 5071643 (1991-12-01), Yu et al.
patent: 5085033 (1992-02-01), Graham
patent: 5431916 (1995-07-01), White
Derwent Abstract of JP 63-222121 (WPI Acc No.: 88-303260/43) Sep. 1988.
Database WPI, Section Ch, Week 9240, Derwent Pub. Ltd., London, G.B.; Class A, p. 96, AN 92-328089, Abstract of JP 04 235 916 A (Aug. 25, 1992).
Remington's Pharmaceutical Sciences, 18th Ed., Chapter 83, pp. 1539-1540 (1990).

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