Filariid anti-P22U antibodies

Details Filariid anti-P22U antibodies Filariid anti-P22U antibodies

2005-08-30

2005-08-30

Swartz, Rodney P (Department: 1645)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds antigen or epitope whose amino acid sequence is...

C424S151100, C424S163100, C424S164100, C424S184100, C424S185100, C530S300000, C530S350000, C530S387100, C530S387900, C536S023100, C536S023700

Reexamination Certificate

active

06936247

ABSTRACT:
The present invention relates to isolated parasitic helminth nucleic acid sequences capable of hybridizing, under stringent conditions, to at least a portion ofD. immitisnucleic acid sequence p4 and/or to at least a portion ofD. immitisnucleic acid sequence p22U; to isolated parasitic helminth proteins that are encoded by such parasitic helminth nucleic acid sequences and that are capable of selectively binding to at least one component of immune serum capable of inhibiting helminth development; and to antibodies raised against such isolated parasitic helminth proteins. The present invention also relates to therapeutic compositions comprising such isolated nucleic acid sequences, proteins and/or antibodies. The present invention also includes methods to produce and use such nucleic acids, proteins, antibodies and therapeutic compositions capable of protecting animals from parasitic helminth infection and, particularly, from heartworm, infection.

REFERENCES:
patent: 4842999 (1989-06-01), Fuller et al.
patent: 0057599 (1988-03-01), None
Tulloch, G.S., et al, “Prepatent clinical, pathologic, and serologic changes in dogs infected withDirofilaria immitisand treated with diethylcarbamazine”, Amer. J. Vet. Res., vol. 31, No. 3, pages 437-448, Mar. 1970.
Abraham et al.,J. Parasitol.,77(2):254-257 (1991).
Abraham et al.,J. Parasitol.,76(4):523-528 (1990).
Abraham et al.,Exp. Parasitol.,70:314-322 (1990).
Abraham et al.,J. Parasitol.74(2):275-282 (1988).
Amiri et al.,Mol. Biochem. Parasitol.,28:113-120 (1988).
Awobuluyi et al., 38th Annual Meeting,Am. J. Trop. Med. Hyg.,p.139, Abstract #150, Dec. 1989.
Bianco, et al.,Mol. Biochem. Parasitol.,39:203-212 (1990).
Blair, et al., “Immunization of Dogs AgainstDirofilaria immitisby Means of Chemically Abbreviated Infections”, 1982,Fifth International Congress of Parasitol.,Toronto, Canada, Aug.
Boyer, et al., 39th Annual Meeting,Am. J. Trop. Med. Hyg.,p. 169, Abstract #221, Nov. 1990.
Chomczynski, et al.,Anal. Biochem.,162:156-159 (1987).
Coleman, et al.,J. Infect. Dis.,154(1):33-39 (1986).
Culpepper, et al.,Mol. Biochem. Parasitol.,54:51-62 (1992).
Dalton, et al.,Mol. Biochem. Parasitol.,35:161-166 (1989).
Davis, et al., 37th Annual Meeting,Am. Soc. Trop. Med. Hyg.,p. 256, Abstract #404 (1988).
Delves, et al.,J. Parasitol.,99:99-104 (1989).
Denham,Inter. J. Nucl. Med. Biol.,7:105-111 (1980).
Frank, et al.,J. Parasitol.,77(6):950-956 (1991).
Frank Dissertation, 1992, Characterization and Cloning of Molt-Associated Excretory-Secretory Proteins ofDirofilaria immitis.
Freedman et al., The 39th Annual Meeting of the American Society of Tropical Medicine and Hygiene, p. 83, Abstract #20.
Fujita,Japan. J. Med. Sci. Biol.,28:139-149 (1975).
Gamble, et al.,Mol. Biochem. Parasitol.,33:49-58 (1989).
Grieve et al.,Pharmaceutical Biotechnology,6:737-68, 1995 (Abstract only).
Grieve, et al.,J. Immunol.,148(8):2511-2515 (1992).
Grieve, “Potential for Immunoprophylaxis Against Heartworm (Dirofilaria immitis) Infection”,Proc. Heartworm Symp.,pp. 187-190 (1989).
Grieve, et al.,Am. J. Trop. Med. Hyg.,39(4):373-379 (1988).
Grieve, et al.,Epidem. Rev.,5:220-246 (1983).
Hewick, et al.,J. Biol. Chem.,256(15):7990-7997 (1981).
Hotez, et al.,J. Biol. Chem.,260(12):7343-7348 (1985).
Ibrahim, et al.,J. Parasitol.,99:89-97 (1989).
Jwo, et al.,Am. J. Trop. Med. Hyg.,41(5):553-562 (1989).
Kassis, et al.,J. Immunol.,123(4):1659-1662 (1979).
Lackey, et al.,Exp. Parasitol.,68:176-185 (1989).
Lal, et al.,J. Immunol.,140:2032-2038 (1988).
Maki, et al.,J. Helminthol.,60:31-37 (1986).
McKerrow, et al.,Biochem J.,231:47-51 (1985).
McKerrow, et al.,Exp. Parasitol.,53:249-254 (1982).
McReynolds, et al., 38th Annual Meeting,Am. J. Trop. Med. Hyg.,pp. 173-174, Abstract #233, Dec. 1989.
McReynolds, et al., 38th Annual Meeting,Am. J. Trop. Med. Hyg.,p. 295, Abstract #445, Dec. 1989.
Mehta et al., The 39th Annual Meeting of the American Society of Tropical Medicine and Hygiene, p. 166,83, Abstract #214.
Mok, et al.,Mol. Biochem. Parasitol.,31:173-182 (1988).
Noble, et al., “Phylum Nematoda”, pp. 256-322, 1982 (See p. 256),Parasitol.: The Biology of Animal Parasites,Section V.
Parab, et al.,J. Immunol.,64:169-174 (1988).
Petralanda, et al.,Mol. Biochem. Parasitol.,19:51-59 (1986).
Philipp, et al.,J. Immunol.,136(7):2621-2627 (1986).
Richer, et al.,Exp. Parasitol.,75:213-222 (1992).
Robertson, et al.,Exp. Parasitol.,69:30-36 (1989).
Rogers,J. Parasitol.,12(6):495-502 (1982).
Scott, et al.,Acta Tropica,47:339-353 (1990).
Sher, et al.,J. Parasitol.,70:347-357 (1975).
Sim, et al.,Trans. Roy. Soc. Trop. Med. Hyg.,76(3):362-370 (1982).
Strosberg, et al.,Current Opin. In Biotech.,2:30-36 (1991).
Tamashiro, et al.,J. Parasitol,73:149-154 (1987).
Tanner, et al.,Trans. Roy. Soc. Trop. Med. Hyg.,75(1):173-174 (1981).
Wang, et al.,J. Parent. Sci. Tech.,42:S3-S26 (1988).
Willadsen, et al.,J. Immunol.,143: 1346-1351 (1989).
Wolff, et al.,Science,247:1462-1468 (1990).
Wong et al.,Exp. Parasitol.,35:465-474 (1974).
Young, et al.,Proc. Natl. Acad. Sci. USA,80:1194-1198 (1983).

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