Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1994-09-01
2000-03-14
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242531, 435 71, 435 691, 435 693, 435 911, 4352523, 4352531, 435320, 4353251, 536 221, 536 231, 536 237, 536 2432, 53612432, A61K 3910, G01N 3353, C12P 2106, C12P 1934
Patent
active
060369604
ABSTRACT:
Nucleic acid and protein compositions are provided from B. pertussis which may find use in diagnosis, prevention and therapy of whooping cough. Particularly, an open reading frame encoding filamentous hemagglutinin precursors provided, with the intact protein for the filamentous hemagglutinin portion thereof, can be expressed in a wide variety of hosts, for use in the production of antibodies, for immunodiagnosis or therapy, or as vaccines for prophylactic purposes.
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Domenighini Mario
Falkow Stanley
Rappuoli Rino
Relman David A.
Hines Ja-Na A.
Housel James C.
Trecartin Richard F.
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