Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1983-01-24
1984-12-04
Wiseman, Thomas
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435 68, 435 70, 435 91, 435254, 435317, 935 24, 935 68, 935 72, 935 73, C12N 1500, C12N 114, C12N 100, C12P 2100, C12P 2102, C12P 1934
Patent
active
044865333
ABSTRACT:
A functional extrachromosomal element capable of replication in filamentous fungi is provided. The extrachromosomal element employs (1) a mitochondrial replicating element or (2) a lower organism replication sequence recognized by the fungus, in combination with foreign DNA to provide replication, transcription, and translation of foreign regulatory elements and genes. The extrachromosomal element is exemplified by a mitochondrial replicating system from Neurospora.
The cell strain E. coli HB101 containing the plasmid pALS-1-1 has been deposited at the A.T.C.C. on July 13, 1982, for patent purposes and given the designation ATCC 39157.
The cell strain E. coli HB101 containing the plasmid pALS-2 has been deposited at the A.T.C.C. on July 13, 1982, for patent purposes and given the designation ATCC 39158.
REFERENCES:
Lambowitz et al.: J. Bacteriology 108, 1087 (1971).
Stohl et al.: Nucl. Acids Res. 10, 1439 (1982).
Collins et al.: Cell 443 (1981).
Stahl et al.: Molec. Gen. Genet. 178, 639 (1980).
Zakian: Proc. Natl. Acad. Sci. USA 78, 3128 (1981).
Martinell James
Rowland Bertram I.
St. Louis University
Wiseman Thomas
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