Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems
Reexamination Certificate
2007-02-13
2007-02-13
Pezzuto, Robert E. (Department: 3766)
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Electrical therapeutic systems
C607S122000, C607S127000, C607S131000, C606S032000, C606S039000, C606S048000
Reexamination Certificate
active
10403636
ABSTRACT:
Improved pacing thresholds for capturing the heart are achieved by forming a discontinuity in the cardiac tissue of the heart chamber, disposing a pacing electrode at a distance less than a space constant of the cardiac tissue from the discontinuity in the cardiac tissue, and applying a stimulus of a first polarity at an energy insufficient to cause the directly stimulated tissue adjacent to the pacing electrode to propagate a depolarization wave through the cardiac tissue mass of the heart chamber but sufficient to induce a transmembrane potential change at the tissue adjacent to the discontinuity that results in a propagated wave front. Thus, pacing energy is advantageously reduced.
REFERENCES:
patent: 4357946 (1982-11-01), Dutcher et al.
patent: 4548203 (1985-10-01), Tacker et al.
patent: 5154183 (1992-10-01), Kreyenhagen et al.
patent: 5522874 (1996-06-01), Gates
patent: 5545201 (1996-08-01), Helland et al.
patent: 5964754 (1999-10-01), Osypka
Fast, Vladimir G., et al., Activation of Cardiac Tissue by Extracellular Electrical Shocks: Formation of ‘Secondary Sources’ at Intercellular Clefts in Monolayers of Cultured Myocytes, Circulation Research, vol. 82(3), Feb. 23, 1998, pp. 375-385.
Newton, Jonathan C., et al., “Review of Mechanisms by Which Electrical Stimulation Alters the Transmembrane Potential”,Cardiovascular Electrophysiology, 1999, Feb. 10(2), 234-243.
Sobie, Eric A., et al., “A Generalized Activating Function for Predicting Vitual Electrodes in Cardiac Tissue”,Biophysical Journal, vol. 73, Sep. 1997, pp. 1410-1423.
Neunlist, Michel, et al., “Spatial Distribution of Cardiac Transmembrane Potentials Around an Extracellular Electrode: Dependence on Fiber Orientation”,Biophysical Journal, vol. 68, Jun. 1995, pp. 2310-2322.
Dekker, Egbart, “Direct Current Make and Break Thresholds for Pacemaker Electroes on the Canine Ventricle”,Circulation Research, vol. XXVII, Nov. 1970, pp. 811-823.
Milburn, Tracy, et al., “The Temperature Dependence of Conductance of the Sodium Channel: Implications for Mechanisms of Ion Permeation”,Receptors and Channels, 1995, vol. 3, pp. 201-211.
Sepulveda, Nestor, et al., “Electric and Magnetic Fields from Two-Dimensional Anisotropic Bisyncytia”,Biophysical Journal, vol. 51, Apr. 1987, pp. 557-568.
Knisley, Stephen B., et al., “Virtual Electrode Effects in Myocardial Fibers”,Biophysical Journal, vol. 66, Mar. 1994, pp. 719-728.
Nagatomo, Toshihisa, et al., Temperature Dependence of Early and Late Currents in Human Cardiac Wild-type and Long Q-T ΔKPQ NA+ Channels,The American Physiological Society, 1998, pp. H2016-H2024.
Fast, Vladimir G., et al., “Activation of Cardiac Tissue by Extracellular Electrical Shocks: Formation of ‘Secondary Sources’ at Intercellular Clefts in Monolayers of Cultured Myocytes”,Circulation Research, vol. 82(3), Feb. 23, 1998, pp. 375-385.
Hidden-Lucent, Franscoise, et al., “Low Chronic Pacing Thresholds of Steroid-Eluting Active-Fixation Ventricular Pacemaker Leads: A Useful Alternative to Passive-Fixation Leads”,PACE, vol. 23, Nov. 2000 Part II, pp. 1798-1800.
Roth, Bradley, J., et al. “A Bidomain Model for the Extracellular Potential and Magnetic Field of Cardiac Tissue”,IEEE, 1986, pp. 467-469.
Watanabe, Toshifumi, et al., “Ventricular Action Potentials, Ventricular Extracellular Potentials, and the ECG of Guinea Pig”,Circulation Research, vol. 57, No. 3, Sep. 1985, pp. 362-373.
Sharma Vinod
Zhou Xiaohong
Bertram Eric D.
Girma Wolde-Michael
Pezzuto Robert E.
Soldner Michael C.
LandOfFree
Field stimulation about a discontinuity of the myocardium to... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Field stimulation about a discontinuity of the myocardium to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Field stimulation about a discontinuity of the myocardium to... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3868192