Image analysis – Applications – Biomedical applications
Patent
1994-09-20
1998-05-26
Boudreau, Leo
Image analysis
Applications
Biomedical applications
382128, G06K 900
Patent
active
057579547
ABSTRACT:
Field of views of a slide are examined to assess the likelihood of existence of detectable single cells, groups, and thick groups of cells to locate objects of interest by an automated microscope. The FOV features consists of features selected from the distribution profiles of size, shape, layout arrangement, texture and density of all objects within a FOV which are compared against pre-determined criteria.
Each field of view is assigned a likelihood value based on FOV features. Areas that are blank, or contain air bubbles, or are too dense for analysis are identified and excluded for further analysis. Each FOV is ranked according to its likelihood of containing SIL (Squamous Intraepithelial Lesion) cells or cell groups of interest. These results, such as SIL, single cell ranking, group ranking are used to arrange the further examination of FOVs in a priority order.
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Kuan Chih-Chau L.
Lee Shih-Jong J.
Rosenlof Mikel D.
Schmidt Robert C.
Boudreau Leo
Mehta Bhavesh
Moffa Emil
NeoPath, Inc.
Sun Hans I.
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