Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge
Patent
1990-11-30
1992-02-18
Niebling, John
Chemistry: electrical and wave energy
Processes and products
Electrostatic field or electrical discharge
204299R, B01D 5702
Patent
active
050890999
ABSTRACT:
An improved electroinjection method of introducing a sample having positive and negative ions into a capillary column for CE or CZE process by introducing a short plug of a low concentration buffer before introducing the sample into the column which results in increasing amount of charged ions of the sample introduced in the capillary column due to increasing the electric field at the injection point. A method for efficiently introducing both positive and negative ions is also shown.
REFERENCES:
patent: 4675300 (1987-06-01), Zare et al.
patent: 4909919 (1990-03-01), Morris et al.
Gordon, et al, "Capillary Electrophoresis," Science, 242 (1988) 224-228.
Hjerten et al. "Some Aspects of the Use of `Continuous` and `Discontinuous` Buffer Systems in Polyacrylamide Gel Electrophoresis," Analytical Biochemistry, 11(1965) 219-223.
Hjerten, Stellan, "High Performance Electrophoresis: the Electrophoretic Counterpart of High-Performance Liquid Chromatography," Journal of Chromatography, 270 (1983) 1-6.
Huang et al., "Bias in Quantitative Capillary Zone Electrophoresis Caused by Electrokinetic Sample Injection," Anal. Chem., 60(1988) 375-377.
Gross et al., "Indirect Fluorimetric Detection and Quantification in Capillary Zone Electrophoresis of Inorganic Anions and Nucleotides," Journal of Chromatography, 480 (1989) 169-178.
Morning et al., "Analytical Aspects of an Automated Capillary Electrophoresis System," IC-GC, vol. 8, No. 1 (1989) 34-46.
Jorgenson et al., "Capillary Zone Electrophoresis," Science, 222 (1983) 266-272.
Jorgenson et al., "Zone Electrophoresis in Open-Tubular Glass Capillaries," Analytical Chemistry, vol. 53, No. 8 (1981) 1298-1302.
Huang et al., "Analysis of Factors Causing Peak Broadening in Capillary Zone Electrophoresis," Journal of Chromatography, 480 (1989) 95-110.
Rose et al., "Characterization and Automation of Sample Introduction Methods for Capillary Zone Electrophoresis," Anal. Chem., 60 (1988) 642-648.
Mikkers et al., "Concentration Distributions in Free Zone Electrophoresis," Journal of Chromatography, 169 (1979) 1-10.
Huang et al., "Effect of Electrolyte and Sample Concentration on the Relationship Between Sensitivity and Resolution in Capillary Zone Electrophoresis Using Conductivity Detection," Journal of Chromatography, 480 (1989) 285-288.
Burgi Dean S.
Chien Ring-Ling
Koestner Caroline
Niebling John
Novack Sheri M.
Sgarbossa Peter J.
Varian Associates Inc.
LandOfFree
Field amplified polarity switching sample injection in capillary does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Field amplified polarity switching sample injection in capillary, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Field amplified polarity switching sample injection in capillary will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1820507