Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2010-01-28
2011-12-13
Allen, Marianne P (Department: 1647)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
Reexamination Certificate
active
08076289
ABSTRACT:
A pharmaceutical preparation comprising a hepatocyte growth factor or a DNA molecule encoding the same and the like according to the present invention can suppress the fibrosis of a transplanted organ after organ transplantation. The present invention is useful in the fields of organ transplantation and regeneration therapy.
REFERENCES:
patent: 5776464 (1998-07-01), Nakamura et al.
patent: 6099841 (2000-08-01), Hilian et al.
patent: 6699837 (2004-03-01), Nakamura et al.
patent: 7563768 (2009-07-01), Nakamura et al.
patent: 1 036 566 (2000-09-01), None
patent: 7-258111 (1995-10-01), None
patent: 7-300426 (1995-11-01), None
patent: 10-194986 (1998-07-01), None
patent: 2000-239182 (2000-09-01), None
patent: 96/40914 (1996-12-01), None
patent: 01/26694 (2001-04-01), None
patent: 02/05840 (2002-01-01), None
H. Tashiro et al., “Hepatocyte Growth Factor Prevents Chronic Allograft Dysfunction in Liver-Transplanted Rats”,Transplantation, vol. 76, No. 5, pp. 761-765, Sep. 15, 2003.
K. Yamaura et al., “Suppression of Acute and Chronic Rejection by Hepatocyte Growth Factor in a Murine Model of Cardiac Transplantation”,Circulation, vol. 110, No. 12, pp. 1650-1657, published on the internet on Sep. 13, 2004 at http://circ.ahajournals.org/.
K. Yamaura et al., “Suppression of Acute and Chronic Rejection by Hepatocyte Growth Factor in a Murine Model of Cardiac Transplantation”,Circulation, vol. 110, No. 12, pp. 1650-1657, Sep. 21, 2004.
Y. Isaka et al., “Electroporation-mediated HGF gene transfection protected the kidney against graft injury”,Gene Therapy(2005), vol. 12, No. 10, pp. 815-820.
I. Herrero-Fresneda et al., “HGF gene therapy attenuates renal allograft scarring by preventing the profibrotic inflammatory-induced mechanisms”,Kidney International Society of Nephrology(2006), vol. 70, No. 2, pp. 265-274.
S. Mizuno et al., “Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease”,The Journal of Clinical Investigation(1998), vol. 101, No. 9, pp. 1827-1834.
K. Yazawa et al., “Direct transfer of hepatocyte growth factor gene into kidney suppresses cyclosporine A nephrotoxicity in rats”,Nephrology Dialysis Transplantation(2004), vol. 19, No. 4, pp. 812-816.
Amano Jun
Ito Ken-ichi
Matsumoto Kunio
Nakamura Toshikazu
Yamaura Kazuhiro
Allen Marianne P
Kringle Pharma Inc.
Wenderoth , Lind & Ponack, L.L.P.
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