Fibronectin-physiologically active substance complex and method

Details Fibronectin-physiologically active substance complex and method Fibronectin-physiologically active substance complex and method

1984-01-23

1985-12-24

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

260112B, 514 21, C07G 700, A61K 3516, A61K 3704

Patent

active

045605564

ABSTRACT:
Physiologically active substances such as antibiotics can preferentially be carried to a morbid part, for example, injured tissue and neoplastic cell proliferation site by administering its complex with fibronectin to repair the morbid part. The complex is prepared by the reaction between the physiologically active substance and the fibronectin with or without intervention of a protein cross-linking agent.

REFERENCES:
patent: 4093607 (1978-06-01), Sela et al.
patent: 4210580 (1980-07-01), Amrani
patent: 4315906 (1982-02-01), Gelder
patent: 4341764 (1982-07-01), Wallace et al.
patent: 4376765 (1983-03-01), Trouet et al.
patent: 4391749 (1983-07-01), Engvall et al.
patent: 4440679 (1984-04-01), Fernandes et al.

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