Fibronectin-dextran-drug complex and method of preparation there

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis

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Details

530392, 530410, 530813, 514 21, 514 8, C07G 700, A61K 3516, A61K 3704, A61K 3172

Patent

active

045871221

ABSTRACT:
The drug such as antitumor agents or antibiotics can preferentially be carried to a morbid part, for example, injured tissue and tumor site by administering its complex with fibronectin combined through an oxidized dextran to repair the morbid part. The complex is prepared by reacting the drug, an oxidized dextran having a cleaved structure of aldohexopyranose ring, and fibronectin.

REFERENCES:
patent: 4210580 (1980-07-01), Amrani
patent: 4315906 (1982-02-01), Gelder
patent: 4341764 (1982-07-01), Wallace et al.
patent: 4376765 (1983-03-01), Trovet et al.
patent: 4391749 (1983-07-01), Engvall et al.

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