Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2007-05-29
2007-05-29
Saoud, Christine J. (Department: 1647)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S069100, C435S320100, C435S243000, C435S325000, C536S023100, C536S023510, C530S399000
Reexamination Certificate
active
09901938
ABSTRACT:
The invention relates to novel nucleic acids encoding a fibroblast growth factor-23(FGF23) and proteins encoded thereby, mutations in which are associated with autosomal dominant rickets (ADHR). The invention further relates to methods of diagnosing and treating hypophosphatemic and hyperphosphatemic disorders comprising inhibiting or stimulating, respectively, the biological activity of FGF23 in a patient. The invention also relates to methods of treating osteoporosis, dermatomyositis, and coronary artery disease comprising stimulating the biological activity of FGF23 in a patient.
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Econs Michael
Meitinger Thomas
Strom Tim Matthias
White Ken
Advanced Research and Technology Institute
Drinker Biddle & Gardner Carton
Ludwig-Maximilians-Universitat Muchen
Saoud Christine J.
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