Fibrinolytic substances

Details Fibrinolytic substances Fibrinolytic substances

1975-11-03

1977-08-02

Shapiro, Lionel M.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424106, 195 62, 195 66B, C07C 7026, A61K 3748

Patent

active

040396584

ABSTRACT:
A new fibrinolytic enzymatic product having also anticoagulant properties is recovered from bile. It can be further purified to yield several fractions, all having similar activities, their molecular weights varying between about 5,000 and 50,000. The product or its fibrinolytically active derivatives are used to dissolve fibrin and inhibit blood coagulation in vivo or in vitro.

REFERENCES:
patent: 3657416 (1972-04-01), Reid et al.
patent: 3713981 (1973-01-01), Broadbent et al.
Katsuki et al., Chemical Abstracts, Oct. 1962, vol. 57, 8881 h.

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