Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1988-12-14
1991-12-10
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 13, 435 771, 435184, G01N 33573, C12Q 156, C12N 999
Patent
active
050717456
ABSTRACT:
Assays and reagents for the determination of factors involved in fibrinolysis, wherein the assays involve the measurement of detectably labelled fibrin products which are released after digestion of a labelled fibrin complex prepared by adding soluble fibrinogen to solid-phase fibrinogen in the presence of thrombin, at least one of the fibrinogens being labelled. The label is preferably an enzyme label.
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G. A. Beard et al., "Ulrasensitive Enzyme Linked Coagulator Assay (ELCA) of Factor V/Va", J. Cell Biology 107:828A (1988).
Doellgast and Rothberger, "Enzyme-Linked Coagulation Assay: A Clot-Based, Solid-Phase Assay for Thrombin", Analytical Biochemistry (1985) 147:529-534.
Doellgast George J.
Triscott Mark X.
Elcatech, Inc.
Kepplinger Esther L.
Neeley Richard L.
Wortman Donna C.
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