Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-10-14
1994-10-25
Chang, Celia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514305, 514323, 514326, 514538, 546133, 546201, 546208, 546210, 546232, 546233, 546234, 562430, 562439, 562440, 562442, 562454, A61K 31445, C07D21132
Patent
active
053589564
ABSTRACT:
Novel fibrinogen receptor antagonists of the formula: ##STR1## are provided in which the claimed compounds exhibit fibrinogen receptor antagonist activity, inhibit platelet aggregation and are therefore useful in modulating thrombus formation.
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patent: 4622331 (1986-11-01), Jozic
patent: 5030654 (1991-07-01), Barnish
patent: 5064814 (1991-11-01), Klien et al.
Hartman et al "Nonpeptide fibrinogen receptor autagonist. 1. Discovery and design of exosite inhibitors" J. Med. Chem. 35 4640-4642 (1992).
Halczenko Wasyl
Hartman George D.
Chang Celia
Matukaitis Paul D.
Merck & Co. , Inc.
Parr Richard S.
Winokur Mel
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