Fibrinogen receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514331, 546201, 546233, A61K 31445, C07D21128, C07D40112

Patent

active

053210344

ABSTRACT:
Fibrinogen receptor antagonists of the formula: ##STR1## are disclosed for use in inhibiting the binding of fibrinogen to blood platelets and for inhibiting the aggregation of blood platelets.

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Ruoslahti et al, "New Perspective in Cell Adhesion." Science 238 491-496 (1987).
Spatola et al, "Amide Bond Surrogate," Chem. Soc. J. Chem Communication 44(3) 821-833 (1988).

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