Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1989-07-28
1991-06-11
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 16, 530317, 530321, 530329, C07K 512, A61K 3702
Patent
active
050232339
ABSTRACT:
A fibrinogen receptor antagonist of the formula: ##STR1## wherein A, B, C, D, E, R, R.sup.1 and X-Y are preferably defined as follows:
REFERENCES:
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4683291 (1987-07-01), Zimmerman et al.
Pierschbacher et al. (a), J. of Biol. Chem., 1987, 282(86), 17294-17298.
Pierschbacher et al. (b), Proc. Natl. Acad. Sci., 1984, vol. 81, 5985-5988.
Rose et al., Advances in Protein Chem., 1985, vol. 37, 20-45.
Stryer, "Biochemistry", 3rd Ed., W. H. Freeman & Co., N.Y. (1988), pp. 277-278.
Phillips et al., BLOOD, vol. 71, No. 4, Apr. 1988, pp. 831-843.
Ruoslahti et al., Science, vol. 238, Oct. 23 (1987), pp. 491-497.
Ruggeri et al., Proc. Natl. Acad. Sci. USA, vol. 83 (1988), pp. 5708-5712.
Plow et al., Proc. Natl. Acad. Sci. USA, vol. 82 (1985), pp. 8057-8061.
Jost et al., Collection Czech. Chem. Comm., vol. 36 (1971), pp. 234-235.
Jost et al., Collection Czech. Chem. Comm., vol. 39 (1974), pp. 2835-2856.
Blood, vol. 70, No. 1 (July) 1987: pp. 110-115 by Edward F. Plow et al.
Echistatin-Journal Biol. Chem., vol. 263, No. 36, pp. 19827-19832.
Brady Stephen F.
Nutt Ruth F.
Veber Daniel F.
Caruso Charles M.
Lee Lester L.
Maebius Stephen B.
Merck & Co. , Inc.
Parr Richard S.
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