Fibrinogen binding moieties

Details Fibrinogen binding moieties Fibrinogen binding moieties

2006-05-09

2006-05-09

Weber, Jon (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

C530S327000, C530S326000, C530S325000, C530S324000, C530S380000, C514S002600

Reexamination Certificate

active

07041790

ABSTRACT:
Compositions comprising non-naturally occurring fibrinogen binding moieties are described, together with methods of use thereof, e.g., for detecting or isolating fibrinogen molecules in a solution, for blood circulation imaging, and for linking therapeutics or other molecules to fibrinogen. Preferred binding peptides having a high affinity for fibrinogen are particularly disclosed.

REFERENCES:
patent: 5116944 (1992-05-01), Sivam et al.
patent: 0 395 918 (1990-11-01), None
patent: WO 91/01743 (1991-02-01), None
patent: WO 97/30734 (1997-08-01), None
Russell et al., “Crystal structure studies on fibrinogen and fibrin,” Ann. N.Y. Acad. Sci., 2001; 936(1); pp. 31-43.
International Search Report for PCT/US03/08732 mailed Nov. 4, 2004.

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