Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2005-11-15
2005-11-15
Wax, Robert A. (Department: 1653)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S381000, C530S350000
Reexamination Certificate
active
06965014
ABSTRACT:
This invention describes a bioerodible fibrin material which is obtained by mixing fibrinogen and thrombin reconstituted or diluted with a particular high tonic strength medium, free of calcium. Such a fibrin-based biomaterial develops a tight structure with thin fibers and small pore size suitable for use as an anti-adhesion barrier. In this invention, thrombin is no longer the variable which governs the tightness and the porosity of the fibrin material obtained, but still controls the clotting time. The mechanical behavior, high-water capacity, and releasable retention properties for therapeutic agents of this fibrin structure causes the fibrin material to be ideally suited for use as a drug delivery device, capable of delivering proteins, hormones, enzymes, antibiotics, antineoplastic agents and even cells for local and systemic treatment of human and non-human patients.
REFERENCES:
patent: 4442655 (1984-04-01), Stroetmann
patent: 5318524 (1994-06-01), Morse et al.
patent: 5989215 (1999-11-01), Delmotte et al.
patent: WO 96/22115 (1996-07-01), None
patent: WO 98/02098 (1998-01-01), None
patent: WO 98/12274 (1998-03-01), None
patent: WO 99/29338 (1999-06-01), None
patent: WO 01/54735 (2001-08-01), None
Delmotte Yves
Diorio James
Baxter International Inc.
Bell Boyd & Lloyd
Guthrie Janice
Mondesi Robert B.
Senniger Powers
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