Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2006-08-15
2006-08-15
Russel, Jeffrey Edwin (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C424S009340, C424S009400, C424S178100, C514S002600, C514S012200, C514S04400A, C530S391300, C530S391700, C530S402000, C530S408000, C530S409000, C530S410000, C536S023100
Reexamination Certificate
active
07091325
ABSTRACT:
A fibrin/fibrinogen binding conjugate for forming a depot for the sustained release of a pharmaceutically active substance from a fibrin clot. The conjugate comprises a fibrin/fibrinogen binding moiety bound to a pharmaceutically active substance either directly or via an intervening substance capturing moiety such as an antibody. The conjugate can also be a recombinant fusion protein comprising a fibrin/fibrinogen binding moiety such as VEGF165C-terminal domain fused to a wound-healing substance such as leptin.
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Fuerst Walter
Helgerson Sam L.
Inman Elisabeth M.
Kneidinger Rudolf
Looker Douglas
Baxter Aktiengesellschaft
Baxter International Inc.
Guthrie Janice
Russel Jeffrey Edwin
Townsend and Townsend and Crew
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