Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-04-04
2006-04-04
Chan, Christina (Department: 1644)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C530S324000, C530S325000, C530S326000, C530S327000, C530S328000, C530S329000, C530S330000, C530S380000
Reexamination Certificate
active
07022485
ABSTRACT:
The invention concerns citrulline polypeptide derived from fibrin useful for diagnosing or treating rheumatoid arthritis.
REFERENCES:
patent: 4281061 (1981-07-01), Zuk et al.
patent: 5821068 (1998-10-01), Soe et al.
patent: 5858723 (1999-01-01), Mueller-Lantzsch et al.
patent: 95 28946 (1995-11-01), None
patent: 98 22503 (1998-05-01), None
Masson-Bessiere et al. Synovial target antigens of antifilaggrin auto antibodies are deiminated forms of fibrin alpha and beta chains. Revue Du Rhumatisme, 66:754, Dec. 1999.
Tarcsa et al. Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural substrates trichohyalin and filaggrin. J Biol Chem.. 271(48):30709-307016, 1996.
Schellekens et al. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest. 101(1):273-281, 1998.
Sebbag Mireille
Serre Guy
Chan Christina
Haddad Maher M.
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Universite Paul Sabatier
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