Fiber optic evanscent wave sensor for immunoassay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 71, 435 74, 435 78, 435 79, 436501, 436518, 436527, 436546, 422 8206, 422 8211, 385 13, 385 30, 356448, C12Q 168, G01N 3353

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054947987

ABSTRACT:
A coupled pair of fiber optic fibers are used an immunoassay device. The fibers are first coupled and then drawn down to a single mode diameter. The coupler senses output ratio change due to chemical, biochemical, bioaffinity, immunogenic-type interactions and other molecular activity occuring within the evanescent field. The fusion joint of the coupler is coated with a first immunoassay component, and then surrounded with a second immunoassay component.

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