Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1996-02-09
1998-09-08
Hutzell, Paula K.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
436501, 435176, 422 8207, 4241301, 4241371, 356345, 385 12, G01N 33543
Patent
active
058044531
ABSTRACT:
A fiber optic bioprobe in which an immobilized biolayer, such as an antigen or antibody, acts as a sensing etalon of a Fabry-Perot interferometer. The bioprobe is used in a system in which a shift in the spectral dispersion pattern, caused by reflected out-of-phase beams, is used to determine a concentration of a substance in a sample solution.
REFERENCES:
patent: 5077210 (1991-12-01), Eigler et al.
"Webster's II New Riverside Dictionary" p. 1212 Houghton Mifflin Company USA, 1994.
Ogert et al., "Detection of Clostridium botulinum Toxin A Using a Fiber Optic-Based Biosensor", Analytical Biochemistry, vol. 205, 1992, pp. 306-312, 1992.
Brecht et al., "Direct monitoring of Antigen-Antibody Interactions by Spectral Interferometry", Sensors and Actuators, vol. B6, 1992, pp. 96-100, 1992.
Brecht, A. et al., "Direct monitoring of antigen-antibody interactions by spectral interferometry", Sensors and Actuators, vol. B6 (1992); pp. 96-100.
Brecht, A. et al., "Interferometric immunoassay in a FIA-System: a sensitive and rapid approach in label-free immunosensing", Biosensors & Bioelectronics, vol. 8 (1993), pp. 387-392.
Brecht, A. et al., "Theoretical and Experimental Detectivity of the RIFS--transducer in Affinity-sensing", Biosensors 94, The Third World Congress on Biosensors: Abstracts, Oral Session, (Jun. 2, 1994), p. 68.
Weber, A. et al., "Fiber-optic fluorimetry in biosensors: comparison between evanescent wave generation and distal-face generation of fluorescent light", Biosensors & Bioelectronics, vol. 7, (1992) pp. 193-197.
Boiarski, A. et al., "Integrated-optic biosensor", SPIE, Fiber Optic Sensors in Medical Diagnostics, vol. 1886 (1993) pp. 15-26.
Fabricius, N. et al., "A gas sensor based on an integrated optical Mach-Zehnder interferometer", Sensors and Actyators, vol. B7 (1992) pp. 672-676.
Cao. L. et al., "Detection of Yersinia pestis Fraction 1 Antigen with a Fiber Optic Biosensor", Journal of Clinical.cndot.Microbiology, vol. 33 No. 2, (Feb. 1995), pp. 336-341.
Rudraraju, S. et al., "Acoustic wave propagation in composite materials: an experimental study", SPIE, vol. 2191, (Jul. 1994) pp. 487-493.
Jorgenson, R. et al., "A Novel Surface Plasmon Resonance BAsed Fiber Optic Sensor Applied to Biochemical Sensing", SPIE, vol. 1886 (1993) pp. 35-48.
Lukosz, W. et al., "Output grating coulers on planar optical waveguides as direct immunosensors", Biosensors & Bioelectronics, vol. 6 (1991) pp. 227-232.
Kimoshita, Y. et al., "Sensing of Herbicide Residues using Surface Plasmon Resonance Technique", The Third World Congress on Biosensors: Abstracts, (1994) p. 257.
Lundstrom, I., et al. "Immunosensors Based on Surface Plasmon Resonance", The Third World Congress on Biosensors: Abstracts, (1991), p. 91.
Daview, R. et al., "An Optical Biosensor System for Molecular Interaction Studies", American Biotechnology Laboratory, (Jul. 1993).
Schneider, I. et al., "Herbicide Detection using Reaction, Centers Integrated into Liposomes Binding to Grating Couplers", The Third World Congress on Biosensors: Abstracts, (1994) p. 271.
Tiefenthaler, K. "Grating Couplers as Label-free Biochemical Waveguide Sensors", Biosensors & Bioelectronics, vol. 8, No. 7-8, pp. xxxv-xxxvii (1993).
Bakalyar Heatha A.
Chen Duan-Jun
Hutzell Paula K.
Michaelson Peter L.
Pokotylo John C.
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