Fiber-optic detectors with terpolymeric analyte-permeable matrix

Details Fiber-optic detectors with terpolymeric analyte-permeable matrix Fiber-optic detectors with terpolymeric analyte-permeable matrix

1995-03-27

1997-06-17

Bovernick, Rodney B.

Optical waveguides

Optical waveguide sensor

422 8206, 422 8207, 128634, G02B 600, G01N 2164

Patent

active

056404700

ABSTRACT:
The invention provides fiber-optic detectors with rapid response times for measuring analytes in aqueous solutions, including blood. The detectors, because of their size, accuracy, and sterilizability may be used in vitro. In a preferred embodiment, pellets comprising a unique, permeable terpolymer of methyl methacrylate, butyl acrylate and methacrylamidopropyltrimethylammonium chloride; and an indicator for an analyte are used as the detecting element of a fiber-optic sensor. Response times for pH testing are better than 150 seconds at t90%. The pellets are easily made by solvent casting techniques and failure rates are low.

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