Fiber optic axial view fluorescence detector and method of use

Details Fiber optic axial view fluorescence detector and method of use Fiber optic axial view fluorescence detector and method of use

1996-06-10

1998-06-09

Snay, Jeffrey

Chemistry: analytical and immunological testing

Optical result

With fluorescence or luminescence

422 8208, 356344, 204452, 204603, G01N 2164

Patent

active

057632774

ABSTRACT:
The present invention system includes an axially oriented end of a fiber optic present in an axially oriented system component bore in which, during use, sample analyte fluorescence is caused to occur. The present invention system and method provides that sample analyte(s) fluorescence inducing energy be entered along a path which is other than essentially parallel to the axially oriented system component bore and that detected fluorescence be transmitted to a detector by the fiber optic. A preferred source of sample analyte(s) fluorescence inducing energy is a laser system, and a preferred method by which to provide sample analyte(s) to the present invention system axially oriented system component bore involves use of electrophoresis.

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Axial-Beam Laser-Excited Fluorescence Detection in Capillary Electrophoresis, Taylor & Yeung, Anal. Chem. 1992, 64.
Laser Fluorescence Detector for Capillary Electrophoresis, Yeung et al., J. Chromatography, 608 (1992).

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