Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-04-04
2006-04-04
Kerr, Kathleen (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S069100, C435S320100, C435S252300, C435S254110, C435S419000, C435S325000, C536S023100, C536S023500
Reexamination Certificate
active
07022474
ABSTRACT:
Novel fetal genes (fls353 and fls485) have been successfully isolated from human fetal liver-derived cDNAs. These genes were specifically expressed in tissues including fetal tissues which are thought to contain a large number of undifferentiated cells and actively differentiating/proliferating cells. High levels of expression of these genes were observed also in a variety of cancer cells. The proteins and genes encoding the proteins can be used as the tool for developing drugs for the treatment of tumors.
REFERENCES:
patent: 2002/0115599 (2002-08-01), Vernos et al.
patent: WO 99/04265 (1999-01-01), None
patent: WO 99/37788 (1999-07-01), None
patent: WO 00/60071 (2000-10-01), None
patent: WO 01/57058 (2001-08-01), None
Ambrosini G et al, Nat Med, 1997, 3(8);917-21.
Su L, et al., Genes Dev, 1993, 7(5);735-48.
Bischoff et al., “A homologue of Drosophilia aurora kinase is oncogenic and amplified in human colorectal cancers”,The EMBO Journal, vol. 17 No. 11 pp. 3052-3065, 1998.
Fram et al., “Immunoenzymatic detection of the new proliferation associated protein p100 by means of a cellular ELISA: specific detection of cells in cell cycle phases S, G2 and M”,Journal of Immunological Methods, 233 pp. 147-153, 1999.
Nezu, J., “Fetal gene preferentially expressed in colorectal cancer”,Database EMBL Online!, Database accession No. AB024704, Apr. 20, 1999.
Tamai et al., “Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1”,FEBS Letters, 419 pp107-111, 1997.
Hufton et al., 1999, FEBS Letters, vol. 463;77-82.
Manda et al., 1999, Genomics, vol. 62;5-14.
Wittmann et al., 2000, J.Cell.Biol., vol. 149, No. 7;1405-1418.
Zhang et al., 1999, Cytogenet Cell Genet, vol. 84; 182-183.
Nezu Jun-Ichi
Ose Asuka
Chugai Seiyaku Kabushiki Kaisha
Fish & Richardson P.C.
Kerr Kathleen
LandOfFree
Fetally expressed gene as a human colon cancer marker does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fetally expressed gene as a human colon cancer marker, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fetally expressed gene as a human colon cancer marker will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3560682