Fetal pulmonary maturity test

Details Fetal pulmonary maturity test Fetal pulmonary maturity test

1984-03-12

1985-10-15

Richman, Barry S.

Chemistry: analytical and immunological testing

Process or composition for determination of physical state...

436 71, 436907, 73 601, 73 61R, G01N 3348, G01N 1300

Patent

active

045474648

ABSTRACT:
A quick and inexpensive test for the detection of fetal pulmonary maturity comprising the steps of acidifying a given volume of amniotic fluid, adding a given volume of an ether, agitating and observing the number of bubbles existing in the ether layer. The number of bubbles existing in the ether layer after a certain observational period may be correlated with the existence of pulmonary immaturity in a fetus.

REFERENCES:
Roux et al., Assessment of Fetal Maturation by the Foam Test, Sep. 15, 1973, _Am. J. Obstet. Gynecol.
Sher et al., Clinical Evaluation of the Quantitative Foam Stability Index _Test, May 1980, Am. College Obstet. Gynecol.
Kulovich et al., The Lung Profile I. Normal Pregnancy, Sep. 1, 1979, _Am. J. Obstet. Gynecol.
Clements et al., Assessment of the Risk of the Respiratory Distress Syndrome _by a Rapid Test for Surfactant in Amniotic Fluid, May 18, 1972, The New _England J. of Medicine.
Torday et al., Saturated Phosphatidylcholine in Amniotic Fluid and Prediction _of the Respiratory Distress Syndrome, 11-08-79, The New England _J. of Medicine.
Tsai et al., Phosphatidylglycerol in 261 Samples of Amniotic Fluid from _Normal and Diabetic Pregnancies, as Measured by a One Dimensional Thin _Layer Chromotography, 1979, Clinical Chemistry.
Olson et al., The Use of Amniotic Fluid Bubble Stability, L/S Ratio and _Creatinine Concentration in the Assessment of Fetal Maturity, Jul 15, 1975, _Am. J. Obstet. Gynecol.
O'Brien et al., Clinical Applicability of Amniotic Fluid Tests for Fetal _Pulmonic Maturity, 1-1-1980, Am. J. Obstet. Gynecol.
Sher et al., Assessing Fetal Lung Maturation by the Foam Stability Index _Test, Dec. 1978, The Am. College of Obstet. Gynecol.
Gluck et al., Diagnosis of the Respiratory Distress Syndrome by _Amniocentesis, Feb. 1, 1971, Amer. J. Obstet. Gynecol.
Collaborative Group, Effect of Antenatal Dexamethasone Administration on _the Prevention of Respiratory Distress Syndrome, Oct. 1, 1981, Am. J. _Obstet. Gynecol.
Zuspan et al., Amniotic Fluid and Fetal Maturity, Jan. 1, 1976, The _Journal of Reproductive Medicine.

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