Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2002-12-14
2009-12-15
Yang, N C (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S285200, C436S518000, C436S524000
Reexamination Certificate
active
07632670
ABSTRACT:
Disclosed is a sensor comprising a substrate, a source contact region, a drain contact region, and the gate oxide of a transistor. A gate electrode is disposed between the gate oxide and a detection electrode made of a nonconducting material. The contact area Asensbetween the gate electrode and the detection electrode is larger than the contact area Agatebetween the gate electrode and the gate oxide, whereby the receptor can be immobilized on the surface of the detection electrode in a technically simple manner while the small contact area Agatebetween the gate electrode and the transistor provides for high sensitivity for detecting the analyte. According to the inventive method for detecting at least one analyte, at least one analyte is brought into contact with a receptor immobilized at the detection electrode so as to modify the electrical charge at the surface of the detection electrode. The analyte is detected by detecting the modified voltage in the transistor.
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Goryll Michael
Lüth Hans
Moers Jürgen
Odenthal Margarete
Offenhäusser Andreas
Forschungszentrum Julich GmbH
Wilford Andrew
Yang N C
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