Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1988-02-25
1993-06-15
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436501, 436510, 436814, 436503, 435 29, G01N 33567, G01N 33566, G01N 3353, C12Q 102, C12Q 100
Patent
active
052197298
ABSTRACT:
A new diagnostic assay of sperm function has been found for infertility treatment and monitoring programs. The hemizona assay (HZA) measures tight binding of human spermatozoa to the human hemizona pellucida.
REFERENCES:
patent: 3992520 (1976-11-01), Gwatkin
Kamada et al (1985) Blocking of human fertalization in vitro . . . Am J Obst Gyn 153(3) 328-331.
Krumins et al (1981) High Affinity binding of lower density . . . Biochem J 196:481-488.
Wassarman (1988) Zona Pellucida glycoprotein Am Rev Biochem 57:415-42.
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Running Title: "Teratozoospermia and zona pellucida binding" by D. R. Franken (Confidential and In Preparation) pp. 1-21.
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Running Title: "Hemizona Assay and T-6 Antibody" by C. C. Coddington et al., pp. 1-20 (Confidential--In Preparation).
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Burkman, et al "The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemzona pellucida to predict fertilization potential" Fertil Steril 49:688, 1988. (1st reference in Oehninger, et al. Fertil. Steril. 51:665, 1989.
Coddington, et al. 5th World Congress on In Vitro Fertilization and Embryo Transfer, Program Supplment Apr. 5-10, 1987 Abstract p. 91 p. 60.
Burkman et al 43rd Annual Meeting of the American Fertility Society, Program Supplement, Abstract 212, Reno 1987.
Nucker Christine M.
Preston D. R.
Serono Laboratories Inc.
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