Liquid purification or separation – Processes – Using magnetic force
Patent
1998-05-20
2000-12-05
Reifsnyder, David A.
Liquid purification or separation
Processes
Using magnetic force
210222, 209214, 356 38, 356246, B01D 3506, G01N 2105
Patent
active
061562084
ABSTRACT:
A ferrographic apparatus and method incorporate a priming operation that moves a priming fluid, in a direction opposite to the flow direction subsequently followed by the sample fluid, through a fluid pathway including the flow chamber. The fluid pathway is configured to facilitate dissipation of any gas bubble introduced into it during the priming operation and to reduce adventitious deposition of specimen material at locations other than the substrate. Sample fluid to be analyzed is added to the reservoir so as to form a bubble-free interface with the priming fluid, and the direction of movement through the flow chamber is reversed. The resulting continuous fluid column is advanced through the fluid pathway so that the sample fluid enters the flow chamber through the inlet port and passes through the magnetic field gradient, exiting through an orifice at the opposite end of the flow chamber serving as the outlet port. The flow chamber of the ferrograph is preferably contained in a deposition cassette comprising the substrate, a gasket and a platen which incorporates an integral fluid reservoir in communication with the inlet port. A pump is preferably configured to move each liquid through the fluid pathway at a distinct flow rate and in a direction according to the function performed by the respective liquid.
REFERENCES:
patent: 3647304 (1972-03-01), Emmel et al.
patent: 4047814 (1977-09-01), Westcott
patent: 5393494 (1995-02-01), Greenfield et al.
patent: 5552885 (1996-09-01), Steen
patent: 5714059 (1998-02-01), Seifert et al.
Desjardins John B.
Seifert William W.
Wenstrup Robert S.
Westcott Vernon C.
Institute Guilfoyle
Reifsnyder David A.
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