Fermentative preparation of L-leucine

Details Fermentative preparation of L-leucine Fermentative preparation of L-leucine

1982-06-16

1983-12-20

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435172, 435840, C12P 1306, C12N 1500, C12R 113

Patent

active

044218532

ABSTRACT:
L-leucine is prepared by cultivation of an analogue-resistant mutant of Brevibacterium thiogenitalis in an aqueous nutrient medium under aerobic conditions. The cultivation is preferably carried out at about 30.degree. C. and at a pH of 5 to 8. L-leucine is recovered from the fermentation broth.

REFERENCES:
patent: 3865690 (1975-02-01), Okumura et al.
patent: 3970519 (1976-07-01), Tsuchida et al.
patent: 4237228 (1980-12-01), Zhdanova et al.

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