Fermentative or enzymatic production of 2-keto-L-gulonic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435843, 435847, C12P 760

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active

045433313

ABSTRACT:
Fermentative or enzymatic production of 2-keto-L-gulonic acid from 2,5-diketo-D-gluconic acid using living or processed mutants, being defective in metabolizing 5-keto-D-gluconic acid and incapable of producing 2-keto-D-gluconic acid. The mutant is derived from 2-keto-L-gluconic acid producing microorganisms of genus Corynebacterium. The production is carried out in the presence of nitrates and/or hydrogen donors in a preliminarily sterilized fermentation broth in which a 2,5-diketo-D-gluconic acid producing microorganism of genus Gluconobacter or Erwinia has been cultivated.

REFERENCES:
patent: Re30872 (1982-02-01), Sonoyama
patent: 3922194 (1975-11-01), Sonoyama
patent: 3959076 (1976-05-01), Sonoyama
patent: 3963574 (1976-06-01), Sonoyama
patent: 3998697 (1976-12-01), Sonoyama

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