Fermentation system and probe detector holder

Details Fermentation system and probe detector holder Fermentation system and probe detector holder

1980-06-11

1982-02-16

Warden, Robert J.

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

435287, 435289, 435290, C12M 134

Patent

active

043159907

ABSTRACT:
A system for the preparation of biological agents can include a vessel in which the biological agents are fermented and in which the fermentation is monitored by a probe detection means. Probe support means are fastened to the wall of the vessel to support the probe detection means with its operative end within the vessel and to provide access from outside the vessel to the output of the probe detection means. The probe support means has a seal-engaging surface at its forwardmost end within the tank. A seal is seated on the probe detection means forwardly of probe support means, and a seal compression member is fastened to the probe support means to compress the seal between the seal-engaging surface of the probe support means, the seal compression means, and the outer surface of the probe detection means to limit the collection of fermentation material to the exposed outer surfaces of the system and permit cleansing and sterilization of the system. In addition, the probe support means can receive a second seal rearwardly of the surface to which the seal compression member is fastened. The seal compression member and the probe support means are adapted so that the end of the seal compression member can also compress the second seal between the probe support means and the end of the seal compression member.

REFERENCES:
patent: 3954565 (1976-05-01), Boiko et al.
patent: 4021120 (1977-05-01), Muller et al.
Dr. Ingold, Specification E 764-31B/70, 1963 Zurich, Switzerland, p. 2096, distributed by Chemapec, Inc., Hoboken, New Jersey.
Dr. Ingold, E-764-20 Pressurized Straight Flow Assembly Unit 764-20/764-31, distributed by Chemapec, Inc., Hoboken, New Jersey.
Dr. W. Ingold, "Pressurized Elbow Flow Assembly Unit" 712-11/764-32.
Dr. Ingold, E764-INF "Industrial pH Measurement Using Pressurized Immersion Assemblies," distributed by Chemapec, Inc., Hoboken, New Jersey, pp. 1-2.
"Ingold Threaded Nipples, Blind Plugs and Protector Shields," distributed by Chemapec, Inc., Hoboken, New Jersey, pp. 1-5.
Arthur H. Thomas Company, Scientific Apparatus and Reagents, Nov. 1968, vol. 5, No. 1, pp. 1-4.

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