Fermentation process for the production of poly(.beta.-hydroxy b

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435142, 435146, 435244, 435829, C12P 752, C12P 744, C12P 742, C12N 138

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active

044330537

ABSTRACT:
Continuous fermentation of Alcaligenes micro-organisms capable of accumulating PHB under limitation of a nutrient required for growth, but not PHB accumulation, so that the PHB content is above 25% by weight. By means of this the carbon in the carbon and energy source, i.e. the substrate, is utilized more efficiently.

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Sonnleitner et al., "Formal Kinetics of PHB Production in A.eutrophus H16 and M.rubra R14", Euro. J. Appl. Microbiol: Biotechnol., 7; 1979; pp. 1-10. _
Schlegel et al., "Formation and Utilization of PHB by Knallgas Bacteria", Nature, vol. 191, Jul. 29, 1961; pp. 463-465.
Hepfinstall et al., "Effect of Growth Conditions on Morphology of Hydrogenomonas facilis and on Yield of a Phospholipoprotein; J. Bacteriology, vol. 110; 1972; pp. 363-367.
Voytovich et al.; "Autotrophic Growth of Hydrogen Bacteria in Continuous Culture", Z.f. Allg. Mikrobiologie; vol. 12, No. 1, 1972; pp. 69-73.
Bongers, Leonard; "Yields of Hydrogenomonos eutropha from Growth on Succinate and Fumarate", J. Bacteriology, May 1970; pp. 598-599.
Gottschalk, G.; Bacterial Metabolism, Springer-Verlog, .COPYRGT.1979, pp. 107, 108.

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